| 產(chǎn)品編號(hào) | bsm-30092M-PE |
| 英文名稱1 | Mouse Anti-human CD3/PE Conjugated antibody |
| 中文名稱 | PE標(biāo)記的小鼠抗人CD3單克隆抗體 |
| 別 名 | CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE. |
| 規(guī)格價(jià)格 | 25T/260元 購(gòu)買 50T/420元 購(gòu)買 100T/680元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 25T 50T 100T |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞表面分子 t-淋巴細(xì)胞 |
| 抗體來(lái)源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | HIT3b |
| 交叉反應(yīng) | Human, |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=10ul/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD3 |
| 亞 型 | Mouse IgG2a, k |
| 純化方法 | affinity purified by Protein G |
| 儲(chǔ) 存 液 | 0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
| 保存條件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 產(chǎn)品介紹 |
background: CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2. Function: The CD3 complex mediates signal transduction. Subunit: he TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Contains 1 ITAM domain. Database links:
Entrez Gene: 916 Human Entrez Gene: 12501 Mouse Omim: 186830 Human SwissProt: P07766 Human SwissProt: P22646 Mouse Unigene: 3003 Human Unigene: 210361 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD3 epsilon 參與T淋巴細(xì)胞介導(dǎo),主要用于免疫排斥方面的研究. |
