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Rabbit Anti-B4GALT6/APC Conjugated antibody (bs-23824R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23824R-APC
英文名稱1 Rabbit Anti-B4GALT6/APC Conjugated antibody
中文名稱 APC標(biāo)記的B4GALT6抗體
別    名 Beta-1,4-Galactosyltransferase 6; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 6; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 6; UDP-Gal:Glucosylceramide Beta-1,4-Galactosyltransferase; UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 6; Beta-1,4-GalTase 6; Beta4Gal-T6; B4Gal-T6; Beta4GalT-VI; B4GT6_HUMAN;   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  合成與降解  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human B4GALT6
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jul 2008]

Function:
Required for the biosynthesis of glycosphingolipids.

Subcellular Location:
Golgi apparatus

Tissue Specificity:
High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood cells.

Similarity:
Belongs to the glycosyltransferase 7 family.

Database links:

Entrez Gene: 9331 Human

Entrez Gene: 56386 Mouse

Omim: 604017 Human

SwissProt: Q9UBX8 Human

SwissProt: Q9WVK5 Mouse

Unigene: 591063 Human

Unigene: 393827 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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