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Rabbit Anti-B4GALT2/BF594 Conjugated antibody (bs-23826R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23826R-BF594
英文名稱1 Rabbit Anti-B4GALT2/BF594 Conjugated antibody
中文名稱 BF594標記的B4GALT2抗體
別    名 Beta-1,4-Galactosyltransferase 2; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 2; UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 2; Beta-1,4-GalTase 2; Beta4Gal-T2; B4Gal-T2; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 2; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 2; UDP-Gal:BetaGlcNAc Beta 1,4-Galactosyltransferase, Polypeptide 2; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase 2; Beta-4-GalT2; EC 2.4.1.-; B4Gal-T3; B4GT2_HUMAN;   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  合成與降解  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human B4GALT2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Function:
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose.

Subcellular Location:
Golgi apparatus

Tissue Specificity:
Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain.

Similarity:
Belongs to the glycosyltransferase 7 family.

Database links:

Entrez Gene: 8704 Human

Entrez Gene: 53418 Mouse

Omim: 604013 Human

SwissProt: O60909 Human

SwissProt: Q9Z2Y2 Mouse

Unigene: 632403 Human

Unigene: 123843 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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