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Rabbit Anti-KATNAL2/AP Conjugated antibody (bs-17081R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17081R-AP
英文名稱 Rabbit Anti-KATNAL2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的KATNAL2蛋白抗體
別    名 DKFZP667C165; Katanin p60 ATPase-containing subunit A-like 2; Katanin p60 subunit A like 2; Katanin p60 subunit A-like 2; KATL2_HUMAN; KATNAL 2; katnal2; MGC33211; p60 katanin like 2; p60 katanin-like 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  染色質和核信號  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Rabbit, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KATNAL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin is a heterodimer complex that severs microtubules in an ATP-dependent manner. The severing of microtubules by the Katanin complex may promote reorganization of cellular microtubule arrays and release of microtubules from the centrosome following nucleation. The Katanin complex is composed of a 60 kDa subunit (Katanin p60 A1) and a 80 kDa accessory protein (Katanin p80 B1). Katanin p60 A1 is responsible for the severing and disassembly of microtubules, while Katanin p80 B1 targets the complex to the centrosome. Katanin p60 A1 and Katanin p80 B1 belong to the AAA ATPase family, which also includes the Katanin p60 A1-like proteins, Katanin p60 AL1 and Katanin p60 AL2.

Function:
Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.

Subcellular Location:
Cytoplasm; cytoskeleton.

Similarity:
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
A-like 2 sub-subfamily.
Contains 1 LisH domain.

Database links:

Entrez Gene: 83473 Human

Entrez Gene: 71206 Mouse

Entrez Gene: 307253 Rat

SwissProt: Q8IYT4 Human

SwissProt: Q9D3R6 Mouse

Unigene: 404137 Human

Unigene: 35803 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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