| 產(chǎn)品編號 | bs-16917R-BF488 |
| 英文名稱 | Rabbit Anti-KCNS2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的電壓門控鉀通道亞基KV9.2抗體 |
| 別 名 | Delayed rectifier K(+) channel alpha subunit 2; Delayed-rectifier K(+) channel alpha subunit 2; Kcns2; KCNS2_HUMAN; KIAA1144; KV9.2; Potassium voltage gated channel subfamily S member 2; Potassium voltage-gated channel subfamily S member 2; Voltage gated potassium channel subunit Kv9.2; Voltage-gated potassium channel subunit Kv9.2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 通道蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNS2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming ?subunits (KV), which include the KV1, KV2, KV3, KV4 and KV9 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV9.2 is a K+ channel subunit that reduces the ion flow and regulates channel activity. It localizes to the cell membrane and, in the absence of KCNB1, KV9.2 may not reach the plasma membrane and may remain in an intracellular compartment. Function: Potassium channel subunit. Modulates channel activity and reduces the ion flow. Subcellular Location: Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1. Tissue Specificity: Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.2/KCNS2 sub-subfamily. Database links: Entrez Gene: 3788 Human Entrez Gene: 16539 Mouse Omim: 602906 Human SwissProt: Q9ULS6 Human SwissProt: O35174 Mouse Unigene: 388045 Human Unigene: 71045 Mouse Unigene: 64498 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
