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Rabbit Anti-ENT2/HRP Conjugated antibody (bs-10550R-HRP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-10550R-HRP
英文名稱 Rabbit Anti-ENT2/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的核苷轉(zhuǎn)運(yùn)蛋白ENT2抗體
別    名 DER12; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; HNP36; Hydrophobic nucleolar protein, 36 kDa; SLC29A2; solute carrier family 29 (nucleoside transporters), member 29; Solute carrier family 29 member 2; S29A2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENT2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]

Function:
ENT2 mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. It is less sensitive than ENT1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.

Subcellular Location:
Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells.

Tissue Specificity:
Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues.

Similarity:
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.

Database links:

Entrez Gene: 3177 Human

Entrez Gene: 13340 Mouse

Entrez Gene: 65194 Rat

Omim: 602110 Human

SwissProt: Q14542 Human

SwissProt: Q61672 Mouse

SwissProt: Q9JIT8 Mouse

SwissProt: O54699 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品圖片
Sample: Muscle (Mouse) Lysate at 40 ug Liver (Mouse) Lysate at 40 ug Lung (Mouse) Lysate at 40 ug Primary: Anti-ENT2 (bs-10550R-HRP) at 1/1000 dilution Predicted band size: 50 kD Observed band size: 50 kD
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