| 產(chǎn)品編號 | bs-14027R-APC |
| 英文名稱1 | Rabbit Anti-CPNE3/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的鈣依賴膜結(jié)合蛋白Copine蛋白3抗體 |
| 別 名 | Copine 3; Copine III; Copine-3; Copine3; CopineIII; CPN3; CPNE 3; CPNE3; CPNE3_HUMAN; KIAA0636; PRO1071. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 結(jié)合蛋白 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CPNE3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Copine 3 is a member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Copine 3 is ubiquitously expressed and contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 3 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Differing from other members of the copine family, copine 3 may possess some intrinsic kinase activity. Copine 3 exists as a monomer in the cytosol and undergoes a conformational change upon binding to calcium. Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated on serine and threonine residues. Similarity: Belongs to the copine family. Contains 2 C2 domains. Contains 1 VWFA domain. Database links: Entrez Gene: 8895 Human Entrez Gene: 70568 Mouse Omim: 604207 Human SwissProt: O75131 Human SwissProt: Q8BT60 Mouse Unigene: 191219 Human Unigene: 38390 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
