| 產(chǎn)品編號(hào) | bs-4200R-BF350 |
| 英文名稱1 | Rabbit Anti-Selenium Binding Protein 1/BF350 Conjugated antibody |
| 中文名稱 | BF350標(biāo)記的硒結(jié)合蛋白1抗體 |
| 別 名 | 56 kDa selenium binding protein; 56 kDa selenium-binding protein; hSBP; LPSB; SBP; SBP1; SBP1_HUMAN; SBP56; Selenbp1; Selenbp2; Selenium binding protein 2; Selenium binding protein1; Selenium-binding protein 1; SELNBP1; SP56. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 52kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SBP1/Selenium Binding Protein 1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease. Function: Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. Subunit: Interacts with USP33. Subcellular Location: Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes. Tissue Specificity: Present in liver and colon (at protein level). Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the selenium-binding protein family. Database links: Entrez Gene: 8991 Human Entrez Gene: 20341 Mouse Omim: 604188 Human SwissProt: Q13228 Human SwissProt: P17563 Mouse Unigene: 632460 Human Unigene: 16617 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
