| 產(chǎn)品編號(hào) | bs-2381R-BF488 |
| 英文名稱 | Rabbit Anti-SRP68/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的信號(hào)識(shí)別顆?？贵w |
| 別 名 | Signal recognition particle 68 kDa; Signal recognition particle subunit SRP68; Signal recognition particle 68 kDa protein; SRP 68; Srp68; SRP68_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 染色質(zhì)和核信號(hào) 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 71kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SRP68 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Subunit: Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Subcellular Location: Cytoplasm. Nucleus, nucleolus. Similarity: Belongs to the SRP68 family. Database links: Entrez Gene: 6730 Human Entrez Gene: 217337 Mouse Omim: 604858 Human SwissProt: Q9UHB9 Human SwissProt: Q8BMA6 Mouse Unigene: 514495 Human Unigene: 29655 Mouse Unigene: 68 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 信號(hào)識(shí)別顆粒(Signalrecognitionparticle,SRP)是介導(dǎo)蛋白識(shí)別轉(zhuǎn)運(yùn)其中普遍存在的機(jī)制之一,細(xì)胞內(nèi)蛋白質(zhì)的定向轉(zhuǎn)移是蛋白質(zhì)質(zhì)量數(shù)量控制體系的一個(gè)重要環(huán)節(jié),SRP對(duì)參與這一過(guò)程的功能基因和蛋白,尤其是蛋白的靶向輸送機(jī)制的研究對(duì)揭示細(xì)胞的分化、代謝和病變具有重大的理論意義. |
