CAOPORN成人免费公开,欧美FREESEX黑人又粗又大 ,欧美狠狠入鲁的视频777色,主仆调教SM束缚绳索捆绑

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
抖音无限次短视频老司机,亚洲精品成人区在线观看
Rabbit Anti-Caspase-9/Gold Conjugated antibody (bs-0049R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@www.tjshangbang.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.tjshangbang.com
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0049R-Gold
英文名稱1 Rabbit Anti-Caspase-9/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的活化半胱胺酸蛋白酶蛋白-9抗體
別    名 Caspase-9 subunit p35; Apaf-3; APAF 3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease activating factor 3; Apoptotic protease MCH 6; Apoptotic protease MCH6; CASP 9; CASP9; Caspase 9; Caspase 9 apoptosis related cysteine protease; Caspase 9 precursor; Caspase 9c; Caspase9; Caspase9 subunit p10; ICE LAP6; ICE like apoptotic protease 6; RNCASP9; MCH 6; MCH6; OTTHUMP00000044594; CASP9_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat, Dog,  (predicted: Mouse, Cow, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35/50kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Caspase-9 subunit p35
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Caspase 9 is inhibited by the dominant negative isoform, BclXL, cIAP1, cIAP2, XIAP, and Livin. This caspase becomes activated when recruited to Apaf1/cytochrome c complex, and following cleavage by Apaf1, granzyme B, Caspase 3, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits. Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin.

Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Subunit:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin.

Tissue Specificity:
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.

Post-translational modifications:
Cleavages at Asp-315 by granzyme B and at Asp-330 by caspase-3 generate the two active subunits. Caspase-8 and -10 can also be involved in these processing events.
Phosphorylated at Thr-125 by MAPK1/ERK2. Phosphorylation at Thr-125 is sufficient to block caspase-9 processing and subsequent caspase-3 activation.

Similarity:
Belongs to the peptidase C14A family.
Contains 1 CARD domain.

Database links:

Entrez Gene: 842 Human

Entrez Gene: 12371 Mouse

Entrez Gene: 58918 Rat

Omim: 602234 Human

SwissProt: P55211 Human

SwissProt: Q4FJK5 Mouse

SwissProt: Q920G4 Rat

Unigene: 329502 Human

Unigene: 88829 Mouse

Unigene: 32199 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Caspase-9半胱氨酸蛋白酶家族成員之一,又稱ICE-Lap6(ICE Like apoptotease 6)參與細(xì)胞凋亡過程和細(xì)胞因子的加工過程,在許多胚胎和成人組織中都有分布。此抗體主要用于腫瘤研究。
版權(quán)所有 2004-2026 www.www.tjshangbang.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
欧美日韩一级一区二区三区| 无遮挡无码H纯肉动漫在线观看| 人妻少妇啊灬啊灬用力啊快| 无码人妻一区二区三区免费看成人| 激情无码人妻又粗又大| 日本免费一区二区视频| 老色鬼精品区在线视频| 国产精品日韩欧美在线第3页| 国产精品美女WWW爽爽爽视频| 99久久99久久精品国产片果冻| 中文AV无码人妻一区二区三区| fulao2在线视频免费观看| 日产乱码一区二区三区在线| 善良的翁熄日本中文版的| 亚洲一区AV无码专区在线观看 | 激情无码人妻又粗又大| 在线免费观看国产| 国产一区二区丝袜在线播放| 日韩欧美色视频在线观看| 亚洲精品无码久久久久久久| 96精产国品一二三产品区别| 国产精品青青青高清在线密亚| 国产一区二区三区在线电影| 亚洲中文字幕日产无码成人片| 精品久久久久久久中文字幕| 日韩精品中文字幕少妇| 2021最新在线精品国产| 韩国年轻妈妈的朋友| 国产精品久久久久影院| 黄片毛片在线观看| 玩弄人妻少妇500系列视频| 亚洲 小说 欧美 激情 另类| 日韩电影一区二区三区| 中文字幕日韩欧美一区二区三区| 一本色道久久88亚洲精品综合| 日韩中文字幕精品一区| JAPANESEHD熟女熟妇| 国产精品福利一区二区久久| 四川少妇BBW搡BBBB槡BBBB| 日本理论片韩国理论片免费看| 秘书在办公室被躁到高潮|