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Rabbit Anti-Nociceptin/Gold Conjugated antibody (bs-0075R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0075R-Gold
英文名稱 Rabbit Anti-Nociceptin/Gold Conjugated antibody
中文名稱 膠體金標記的孤菲肽/痛敏肽抗體
別    名 PNOC; N/OFQ; N23K; N23K/N27K; Nociceptin, included; Npnc1; OFQ; OFQ/N; Orphanin FQ; PPNOC; prepronociceptin; Propronociceptin; PNOC_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nociceptin (130-146aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Nociceptin (PNOC) is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Expressed predominantly in the spinal cord and brain, being more abundant in the hypothalamus and striatum. Also found in small amounts in ovary. Belongs to the opioid neuropeptide precursor family.


Function:
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity).

Subcellular Location:
Secreted.

Tissue Specificity:
Predominantly in the brain and spinal cord.

Similarity:
Belongs to the opioid neuropeptide precursor family.

Database links:

Entrez Gene: 5368 Human

Entrez Gene: 18155 Mouse

Entrez Gene: 25516 Rat

Omim: 601459 Human

SwissProt: Q13519 Human

SwissProt: Q64387 Mouse

SwissProt: Q62923 Rat

Unigene: 88218 Human

Unigene: 16347 Mouse

Unigene: 486163 Mouse

Unigene: 87935 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

孤菲肽(Nociceptin又稱為Orphanin FQ; PPNOC; ORL1)是新發(fā)現(xiàn)的一種神經(jīng)肽,由17個氨基酸組成,又稱痛敏肽。消化道腫瘤病人的血漿中OFQ含量明顯高于對照組,尤以結(jié)腸癌、胃癌最為明顯。
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