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Rabbit Anti-NAP1L1/AP Conjugated antibody (bs-1052R-AP)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1052R-AP
英文名稱 Rabbit Anti-NAP1L1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的核小體組裝蛋白1抗體
別    名 NAP1L; FLJ16112; hNRP; HSP22 like protein interacting protein; MGC23410; MGC8688; NAP 1; NAP 1 related protein; NAP 1L; NAP-1 related protein; NAP-1-related protein; NAP1; NAP1 L1; NAP1 related protein; Nap1l1; NAP1L1 protein; NP1L1_HUMAN; NRP; Nucleosome assembly protein 1 like 1; Nucleosome assembly protein 1-like 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAP1L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. The binding of sequence-specific DNA binding proteins to human nucleosome assembly protein 1 may be an important step contributing to the activation of transcription. May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Function:
May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Subcellular Location:
Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:

Entrez Gene: 4673 Human

Entrez Gene: 53605 Mouse

Entrez Gene: 89825 Rat

Omim: 164060 Human

SwissProt: P55209 Human

SwissProt: P28656 Mouse

SwissProt: Q9Z2G8 Rat

Unigene: 524599 Human

Unigene: 695185 Human

Unigene: 290407 Mouse

Unigene: 162938 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核小體組裝蛋白1(NAP-1) 作為核心組蛋白的分子伴蛋白,在進(jìn)化過(guò)程中是相當(dāng)保守的.它通過(guò)幫助核心組蛋白沉積到DNA上來(lái)促進(jìn)核小體的組裝.而大量研究表明,酵母和動(dòng)物中的NAP類似蛋白除了具有核小體組裝能力以外,還有其它多種功能
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