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Rabbit Anti-Omgp/PE-Cy5.5 Conjugated antibody (bs-1200R-PE-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1200R-PE-Cy5.5
英文名稱 Rabbit Anti-Omgp/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的少突細(xì)胞髓磷脂糖蛋白抗體
別    名 olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Cow, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Omgp
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin.

Function:
Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

Subunit:
Binds to RTN4R.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:
Oligodendrocytes and myelin of the central nervous system.

Post-translational modifications:
O-glycosylated in its Ser/Thr-rich repeat domain (Potential).

Similarity:
Contains 8 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 407186 Cow

Entrez Gene: 4974 Human

Entrez Gene: 100172122 Orangutan

Omim: 164345 Human

SwissProt: P23515 Human

Unigene: 113874 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OMgp也是髓鞘糖蛋白的一種,在發(fā)育期促進(jìn)軸突生長(zhǎng),成熟期抑制軸突生長(zhǎng).其抑制作用主要由髓鞘來源的抑制分子的共同受體NgR介導(dǎo),在神經(jīng)營(yíng)養(yǎng)因子受體p75NTR以及小GTP酶Rho等信號(hào)分子的共同參與下完成.
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