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Rabbit Anti-SOD3/BF647 Conjugated antibody (bs-3895R-BF647)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-3895R-BF647
英文名稱(chēng) Rabbit Anti-SOD3/BF647 Conjugated antibody
中文名稱(chēng) BF647標(biāo)記的超氧化物歧化酶3抗體
別    名 EC-SOD; Superoxide Dismutase 3; ALS; ALS1; Cu/Zn superoxide dismutase; EC SOD; Extracellular superoxide dismutase [Cu Zn]; Extracellular superoxide dismutase; Extracellular superoxide dismutase precursor; Homodimer; Indophenoloxidase A; IPOA; Mn superoxide dismutase; SOD 3; SOD; SOD soluble; SOD2; SOD3; Superoxide dismutase 3 extracellular; Superoxide dismutase cystolic; SODE_HUMAN; extracellular superoxide dismutase isoform 1.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOD3 extracellular superoxide dismutase isoform 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]

Function:
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.

Subunit:
Homotetramer.

Subcellular Location:
Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.

Tissue Specificity:
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.

Similarity:
Belongs to the Cu-Zn superoxide dismutase family.

Database links:

Entrez Gene: 6649 Human

Entrez Gene: 20657 Mouse

Entrez Gene: 25352 Rat

Omim: 185490 Human

SwissProt: P08294 Human

SwissProt: O09164 Mouse

SwissProt: Q08420 Rat

Unigene: 2420 Human

Unigene: 2407 Mouse

Unigene: 10358 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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