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Rabbit Anti-DMT1/PE-Cy7 Conjugated antibody (bs-3577R-PE-Cy7)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3577R-PE-Cy7
英文名稱 Rabbit Anti-DMT1/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的金屬離子轉(zhuǎn)運(yùn)體1抗體
別    名 DCT 1; DCT1; Divalent metal transporter 1; DMT 1; DMT1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2; NRAM2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Cow, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DMT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DMT1 is a major transporter of ferrous iron from the intestinal lumen. DMT1 belongs to the family of NRAMP metal ion transporters which function in diverse organisms from bacteria to human. DMT1 (NRAMP2) transports metal ions at the plasma membrane of cells of both the duodenum and in peripheral tissues, and defective DMT1 causes anaemia.

Function:
Actin-bundling protein. May function in mitogen-activated protein kinase pathway.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Heart, brain, lung, skeletal muscle, and kidney.

Post-translational modifications:
Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.

Similarity:
Belongs to the villin/gelsolin family.
Contains 1 HP (headpiece) domain.

Database links:

Entrez Gene: 4891 Human

Entrez Gene: 18174 Mouse

Omim: 600523 Human

SwissProt: P49281 Human

SwissProt: P49282 Mouse

Unigene: 505545 Human

Unigene: 234608 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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