CAOPORN成人免费公开,欧美FREESEX黑人又粗又大 ,欧美狠狠入鲁的视频777色,主仆调教SM束缚绳索捆绑

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
偷偷色噜狠狠狠狠的777米奇,色偷偷888欧美精品久久久,亚洲AV无码乱码国产麻豆穿越
Rabbit Anti-ENAH/Cy5 Conjugated antibody (bs-9660R-Cy5)
~~~促銷,代碼KT202502A~~~
~~~促銷,代碼KT202502B~~~
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@www.tjshangbang.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@www.tjshangbang.com
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9660R-Cy5
英文名稱 Rabbit Anti-ENAH/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的ENAH蛋白抗體
別    名 ENA; Enah; ENAH_HUMAN; MENA; NDPP1; Protein enabled homolog.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENAH/MENA
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
EVL is an Actin-binding protein that belongs to the Mena/VASP protein family. EVL is expressed in filopodial tips and localizes to the edge of the lamellipodia and focal adhesions. In epithelial cells, EVL localizes to the membrane of the lateral domain. EVL contains an N-terminal EVH1 domain, a proline-rich core and a C-terminal EVH2 domain. Via its proline-rich domain, EVL interacts with the SH3 domain of spectrin a II and the LIM domain of TES. EVL is closely related to VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein). Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance; VASP is involved in the maintenance of cyto-architecture by interacting with Actin-like filaments. All three proteins, EVL, Mena and VASP, are involved in cell motility and the regulation of cytoskeletal organization and dynamics.

Function:
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. Required for the actin-based mobility of Listeria monocytogenes.

Subunit:
Homotetramer. Interacts with APBB1IP, APBB1, PFN1 and ROBO4. Isoforms, containing the polyproline-rich regions with PPLP motifs, bind the WW domain of APBB1IP. Isoforms, containing the PPSY motif, bind, in vitro, to the WW2 and WW3 domains of NEDD4 and to the WW1 domain of YAP1. Binds the SH3 domain of BAIAP2-alpha but only after the autoinhibitory region of BAIAP2-alpha has been blocked by interaction with CDC42. Interacts, via the EVH1/WH1 domain, with the Pro-rich domains from VCL, ZYX and Listeria monocytogenes actA and with TES (via LIM domains). The TES LIM domain and the Pro-rich domains from VCL or ZYX compete for the same binding site. Interaction with ZYX is important for targeting ENAH to focal adhesions and enhances production of actin-rich structures at the apical surface of cells. Interacts, through the Pro-rich region, with the C-terminal SH3 domain of DNMPB. Binds GPHN. Interacts with FAT1 (via EVH1 domains). Heterotrimer with TES and ACTL7A.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, filopodium. Cell junction, synapse. Cell junction, focal adhesion. Note=Targeted to the leading edge of lamellipodia and filopodia by MRL family members. Colocalizes at filopodial tips with a number of other proteins including vinculin and zyxlin. Colocalizes with N-WASP at the leading edge. Colocalizes with GPHN and PFN at synapses.

Tissue Specificity:
Expressed in myoepithelia of parotid, breast, bronchial glands and sweat glands. Expressed in colon-rectum muscolaris mucosae epithelium, pancreas acinar ductal epithelium, endometrium epithelium, prostate fibromuscolar stroma and placenta vascular media. Overexpressed in a majority of breast cancer cell lines and primary breast tumor lesions.

Post-translational modifications:
NTN1-induced PKA phosphorylation on Ser-265 directly parallels the formation of filopodial protrusions.
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the Ena/VASP family.
Contains 1 WH1 domain.

Database links:

Entrez Gene: 55740 Human

Entrez Gene: 13800 Mouse

Entrez Gene: 360891 Rat

Omim: 609061 Human

SwissProt: Q8N8S7 Human

SwissProt: Q03173 Mouse

Unigene: 497893 Human

Unigene: 389224 Mouse

Unigene: 87759 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.www.tjshangbang.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲精品国产电影| 日韩精品一区二区三区久久久| 日韩一级理论片| 星空无限传媒一二三区小甜豆| 四虎WWW成人影院观看| CHINESE国产HD中国熟女| 熟女日韩中文字幕18禁| 日韩精品一区二区三区vr| 亚洲ΑV无码一区二区三区四区| 91麻豆精品国产91| 国产精品久久毛片| 亚洲欧美日韩一区在线| 领导边摸边吃奶边做爽在线观看| 国产伦精品一区二区三区免.费| 日韩欧美综合亚洲| 日韩精品视频在线| 国产精品久久久久永久免费看| 国产毛片久久久久久国产毛片| 欧美午夜理伦三级在线观看| 日韩精品中文字幕有码专区| 黑人玩弄漂亮少妇高潮大叫| 欧美日韩国产精品综合在线一| 国产欧美精品久久久久| 调教太平洋TXT下载| 亚瑟天堂久久一区二区影院| 1769国产精品短视频| 久久久久久亚洲av午夜| 丰满熟妇大肉唇张开| 日韩一级二级| 黑人巨大三根一起进hd| 国产FREEXXXX性播放| 亚洲AV成人无码久久A片| 1769国产精品视频免费观看| 亚洲欧美在线视频观看免费| 无人区卡一卡二卡三乱码入口| 国产亚洲欧美夫妻一区| 熟妇高潮精品一区二区三区| 在线视频国产欧美日韩| 欧美日韩精品久久| 色综合天天综合网国产成人网| 欧美激情第1页|