| 產(chǎn)品編號(hào) | bs-1827R-BF488 |
| 英文名稱1 | Rabbit Anti-IL-11/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的白介素11抗體 |
| 別 名 | Interleukin-11; Adipogenesis inhibitory factor; AGIF; IL 11; IL11; Interleukin 11; Oprelvekin; IL11_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 血管內(nèi)皮細(xì)胞 淋巴細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 19kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-11 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy. Function: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Subcellular Location: Secreted. Similarity: Belongs to the IL-6 superfamily. Database links: Entrez Gene: 3589 Human Omim: 147681 Human SwissProt: P20809 Human Unigene: 467304 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白介素11，是一種多向性細(xì)胞因子。很多細(xì)胞都能合成IL11，如：內(nèi)皮細(xì)胞、纖維母細(xì)胞、軟骨細(xì)胞、滑膜細(xì)胞、成骨細(xì)胞、上皮細(xì)胞、神經(jīng)元、胸腺等。正常的血清中，IL11表達(dá)很少或處在檢測(cè)水平之下。對(duì)造血系統(tǒng)的功能包括：干細(xì)胞、巨核細(xì)胞、骨髓細(xì)胞、紅細(xì)胞和B淋巴細(xì)胞的增生和發(fā)育。對(duì)造血系統(tǒng)之外也具有多相性的作用，有些是刺激和促進(jìn)增生，有些是抑制作用。人、大鼠、小鼠的IL-11的前體有199個(gè)氨基酸。成熟形態(tài)為178個(gè)氨基酸。 |
