CAOPORN成人免费公开,欧美FREESEX黑人又粗又大 ,欧美狠狠入鲁的视频777色,主仆调教SM束缚绳索捆绑

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
张雨欣人文艺术欣赏PPT,玩弄白嫩少妇xxxxx性,99精品人妻无码专区在线视频区
Rabbit Anti-HRG beta 1/PE-Cy3 Conjugated antibody (bs-6228R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@www.tjshangbang.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.tjshangbang.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6228R-PE-Cy3
英文名稱1 Rabbit Anti-HRG beta 1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的乳腺癌細(xì)胞分化因子P45抗體
別    名 Neuregulin 1; GGF2; Acetylcholine receptor inducing activity; ARIA; Breast cancer cell differentiation factor p45; GGF; glial growth factor; Heregulin; Heregulin beta1; heregulin, alpha (45kD, ERBB2 p185 activator); HGL; HRG; HRG beta 1A; HRG1; HRGA; NDF; neu differentiation factor; NRG1; sensory and motor neuron derived factor; SMDF; NRG1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuregulin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Jun 2014]

Function:
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

Subunit:
The cytoplasmic domain interacts with the LIM domain region of LIMK1. Interacts with ERBB3 and ERBB4.

Subcellular Location:
Pro-neuregulin-1, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein. Neuregulin-1: Secreted. Isoform 8: Nucleus. Isoform 9: Secreted. Isoform 10: Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Type I isoforms are the predominant forms expressed in the endocardium. Isoform alpha is expressed in breast, ovary, testis, prostate, heart, skeletal muscle, lung, placenta liver, kidney, salivary gland, small intestine and brain, but not in uterus, stomach, pancreas, and spleen. Isoform 3 is the predominant form in mesenchymal cells and in non-neuronal organs, whereas isoform 6 is the major neuronal form. Isoform 8 is expressed in spinal cord and brain. Isoform 9 is the major form in skeletal muscle cells; in the nervous system it is expressed in spinal cord and brain. Also detected in adult heart, placenta, lung, liver, kidney, and pancreas. Isoform 10 is expressed in nervous system: spinal cord motor neurons, dorsal root ganglion neurons, and brain. Predominant isoform expressed in sensory and motor neurons. Not detected in adult heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Not expressed in fetal lung, liver and kidney. Type IV isoforms are brain-specific.

Post-translational modifications:
Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form.
N- and O-glycosylated. Extensive glycosylation precedes the proteolytic cleavage.

DISEASE:
Note=A chromosomal aberration involving NRG1 produces gamma-heregulin. Translocation t(8;11) with ODZ4. The translocation fuses the 5'-end of ODZ4 to NRG1 (isoform 8). The product of this translocation was first thought to be an alternatively spliced isoform. Gamma-heregulin is a soluble activating ligand for the ERBB2-ERBB3 receptor complex and acts as an autocrine growth factor in a specific breast cancer cell line (MDA-MB-175). Not detected in breast carcinoma samples, including ductal, lobular, medullary, and mucinous histological types, neither in other breast cancer cell lines.

Similarity:
Belongs to the neuregulin family.
Contains 1 EGF-like domain.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 3084 Human

Entrez Gene: 211323 Mouse

Omim: 142445 Human

SwissProt: Q02297 Human

Unigene: 453951 Human

Unigene: 668810 Human

Unigene: 153432 Mouse




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

神經(jīng)膠質(zhì)生長因子
版權(quán)所有 2004-2026 www.www.tjshangbang.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
欧美一区二区三区四区精品| 国产成人久久AV免费看| 国内精品久久久久影院老司| 欧美黑人性人禽猛交高清| JAPANESE日本爆乳巨大| 日韩精品一区二区牛| 女人18片毛片60分钟| 色综合欧美在线视频区| 中文字幕被公侵犯的漂亮人妻| 国产一区二区三区美女| 天美传媒MV免费观看| 国产成本人片免费AV| 日韩一级理论片| SM调教贱屁股眼哭叫求饶H| 亚洲国产一区二区三区青草影视| 97精产国品一二三产区| 少妇BBBBBB水水多| 色偷偷888欧美精品久久久| 两个男人吮她的花蒂和奶水视频| 免费床视频大全叫不停欧美| 欧美午夜色视频国产精品| 亚洲男人天堂一区二区三区| 被夫の上司に犯中文字幕| 国产在线拍偷码自揄拍无| 亚洲国产日韩无在线播放| 日本三区精品三级在线电影| 日日麻批免费40分钟无码| 精品性高朝久久久久久久| 中国A级毛片免费观看| 免费伦理片在线观看| 99热门精品一区二区三区无码| 久久国产劲暴∨内射新川| 久久精品WWW人人爽人人| 一本色道久久综合亚洲高| 国产在线观看91精品一区| 一区二区三区中文字幕| 在丈前下药侵犯人妻在线| 亚洲一卡2卡3卡4卡国产网站| 欧美在线视| 日日摸日日碰人妻无码 | 日本高清不卡AⅤ免费网站|