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Rabbit Anti-RERG/AP Conjugated antibody (bs-6091R-AP)
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訂購QQ:  400-901-9800
技術支持:techsupport@www.tjshangbang.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6091R-AP
英文名稱 Rabbit Anti-RERG/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的Ras相關雌激素調(diào)節(jié)生長抑制蛋白
別    名 RAS like estrogen regulated growth inhibitor; Ras related and estrogen regulated growth inhibitor; Ras-related and estrogen-regulated growth inhibitor; Rerg; RERG_HUMAN; Weakly similar to N ras protein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  染色質(zhì)和核信號  信號轉導  轉錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RERG
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation

Function:
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis.

Similarity:
Belongs to the small GTPase superfamily. Ras family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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