| 產(chǎn)品編號(hào) | BIO0965SM |
| 英文名稱 | Anti-EGFR & HER3 Reference Antibody (Duligotuzumab Biosimilar) |
| 別 名 | ERBB1 / EGFR / HER1 & ERBB3 / HER3; Duligotuzumab |
| 抗體來(lái)源 | |
| 克隆類型 | Monoclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 144.78kDa |
| 性 狀 | Lyophilized |
| 亞 型 | IgG-like |
| 純化方法 | Protein A |
| 緩 沖 液 | 100 mM Pro-Ac 20mM Arg pH 5.0 |
| 保存條件 | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | |
| 產(chǎn)品圖片 |
Duligotuzumab bound to 0920-13 Hu-HER3-FL-HEK293-A4 cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Duligotuzumab bound to 0920-13 Hu-HER3-FL-HEK293-A4 cells, and the EC50 was 0.645 nM.
Duligotuzumab bound to EGFR-CHO-K cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Duligotuzumab bound to EGFR-CHO-K cells, and the EC50 was 0.937 nM.
Duligotuzumab bound to HER3 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Duligotuzumab bound to Human-HER3-his, and the EC50 was 0.002 nM.
Duligotuzumab bound to EGFR protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Duligotuzumab bound to Human EGFR-his, and the EC50 was 0.002 nM.
The purity of Anti-EGFR & HER3 Reference Antibody (Duligotuzumab (USAN)) is 100%, determined by SEC-HPLC.
Anti-EGFR & HER3 Reference Antibody (Duligotuzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The detected molecular weight of Anti-EGFR & HER3 Reference Antibody (Duligotuzumab) is 144.47 kDa.
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