| 產(chǎn)品編號(hào) | BIO0064SM |
| 英文名稱 | Anti-human B7-H1 / PD-L1 / CD274 (Durvalumab Biosimilar) |
| 中文名稱 | |
| 抗體來(lái)源 | |
| 克隆類型 | Monoclonal |
| 交叉反應(yīng) | Human,Mouse,Cynomolgus |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 146.32 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Lyophilized |
| 亞 型 | Human IgG1 |
| 純化方法 | Protein A |
| 保存條件 | For long term storage, the produce should be stored at -20°C or lower. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | |
| 產(chǎn)品圖片 |
Durvalumab inhibited the tumor growth of A375 on NOD.SCID mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 61.2% at 5 mpk at D22.
Immobilized cynomolgus / Rhesus macaque B7-H1 / PD-L1 / CD274, Fc Tag Protein at 2 ug/mL can bind Durvalumab ，EC50=0.006186 ug/mL.
Immobilized human PD-L1 His at 2 ug/mL can bind Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (Durvalumab), EC50=0.03756 ug/mL
The purity of Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (durvalumab) is 100%, determined by SEC-HPLC.
Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (durvalumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
|
