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Anti-human ERBB2 / HER2 / CD340 (Trastuzumab Biosimilar) (BIO0037SM)  
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產(chǎn)品編號(hào) BIO0037SM
英文名稱 Anti-human ERBB2 / HER2 / CD340 (Trastuzumab Biosimilar)
中文名稱
抗體來(lái)源
克隆類型 Monoclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 145.36 kDa
檢測(cè)分子量
性    狀 Lyophilized
亞    型 Human IgG1
純化方法 Protein A
保存條件 For long term storage, the produce should be stored at -20°C or lower.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹
產(chǎn)品圖片
Trastuzumab inhibited the tumor growth of BT474 on NCG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 88.5% at 10 mpk at D35.
BT474 cells were stained with Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.3024 ug/mL.
Immobilized human HER2, His at 2 ug/mL can bind Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab), EC50=0.005735 ug/mL.
The purity of Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) is more than 95%, determined by SEC-HPLC.
Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
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