| 產(chǎn)品編號 | bsm-55522R |
| 英文名稱 | S100A4 Recombinant Rabbit mAb |
| 中文名稱 | S100鈣結(jié)合蛋白A4重組兔單抗 |
| 別 名 | 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, S100 calcium binding protein A4 |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | SB100 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1: 500-1: 2000,IHC-P=1: 800-1: 1600,IHC-F=1: 800-1: 1600,IF=1: 800-1: 1600
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 12 kDa |
| 檢測分子量 | 12 |
| 性 狀 | Liquid |
| 免 疫 原 | Recombinant Mouse S100A4 protein |
| 亞 型 | IgG |
| 純化方法 | Affinity Purification |
| 緩 沖 液 | PBS with 100 μg/ml BSA,0.15% ProClin300 and 50% glycerol. |
| 保存條件 | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. SWISS: P07091 Gene ID: 20198 S100A4屬于鈣離子結(jié)合蛋白S100蛋白家族，參與細(xì)胞骨架及細(xì)胞膜的相互作用、鈣離子信號傳遞和細(xì)胞生長及分化等，在細(xì)胞內(nèi)、外均可發(fā)揮作用，增加腫瘤細(xì)胞的運動、侵襲能力，降低細(xì)胞間黏附力，重塑細(xì)胞外基質(zhì)，促進(jìn)細(xì)胞異常增生及血管生成，被稱為轉(zhuǎn)移促進(jìn)基因。 |
