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FSH beta Recombinant Rabbit mAb (bsm-61006R)  
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產(chǎn)品編號 bsm-61006R
英文名稱 FSH beta Recombinant Rabbit mAb
中文名稱 促卵泡刺激素重組兔單抗
別    名 Follicle Stimulating Hormone; Follicle stimulating hormone beta polypeptide; Follicle stimulating hormone beta subunit; Follitropin beta chain; Follitropin beta chain precursor; Follitropin subunit beta; FSH B; FSH-B; FSH-beta; FSHB; FSHbeta.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 1E12
交叉反應 Human (predicted: Rabbit)
產(chǎn)品應用 WB=1:1000-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,IP=1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human FSH beta: 30-84 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Function:
Stimulates development of follicle and spermatogenesis in the reproductive organs.

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

DISEASE:
Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [MIM:229070]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men.

Similarity:
Belongs to the glycoprotein hormones subunit beta family.

Database links:

Entrez Gene: 2488 Human

Entrez Gene: 100008946 Rabbit

Omim: 136530 Human

SwissProt: P01225 Human

SwissProt: Q6IY73 Rabbit

Unigene: 36975 Human



促卵泡激素與黃體生成素統(tǒng)稱促性腺激素具有促進卵泡發(fā)育成熟作用,與黃體生成素一起促進雌激素分泌.
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded Human pituitary gland; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with FSH beta Monoclonal Antibody, Unconjugated(bsm-61006R) at 1:100 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
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