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Rabbit Anti-RAET1G  antibody (bs-21145R)
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產(chǎn)品編號 bs-21145R
英文名稱 Rabbit Anti-RAET1G  antibody
中文名稱 維甲酸早期轉(zhuǎn)錄1G蛋白抗體
別    名 RAET1G; RET1G_HUMAN; Retinoic acid early transcript 1G; Retinoic acid early transcript 1G protein; Retinoic acid early transcript 1G pseudogene; ULBP5.  
研究領域 細胞生物  免疫學  自然殺傷細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAET1G: 131-230/334 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the major histocompatibility complex (MHC) class I family of proteins. Although the encoded protein includes C-terminal transmembrane and cytoplasmic domains, proteolytic processing results in the removal of these domains and subsequent tethering to the plasma membrane by a glycosylphosphatidylinositol (GPI)-anchor. The encoded protein is one of several related ligands of the natural killer group 2, member D (NKG2D) receptor, which functions as an activating receptor in innate and adaptive immunity. This gene is present in a gene cluster on chromosome 6. [provided by RefSeq, Jul 2015]

Function:
Acts as a ligand for the NKG2D receptor and mediates NK cell cytotoxicity via the receptor.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highly expressed in colon and in a number of tumor cell lines.

Similarity:
Belongs to the MHC class I family.

SWISS:
Q6H3X3

Gene ID:
353091

Database links:

Entrez Gene: 404100 Cow

Entrez Gene: 353091 Human

Omim: 609244 Human

SwissProt: Q6H3X3 Human

Unigene: 558792 Human



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