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Rabbit Anti-APOC2  antibody (bs-20271R)
~~~促銷代碼KT202410~~~
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產品編號 bs-20271R
英文名稱 Rabbit Anti-APOC2  antibody
中文名稱 載脂蛋白C2抗體
別    名 APC 2; APC2; Apo CII; APOC 2; ApoC II; APOC2; APOC2 protein; APOC2_HUMAN; ApoCII; Apolipoprotein C II; Apolipoprotein C II precursor; Apolipoprotein C2; ApolipoproteinCII; MGC75082.  
研究領域 腫瘤  心血管  細胞生物  免疫學  信號轉導  脂蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse,Rat)
產品應用 WB=1:500-2000,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 9kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APOC2: 51-97/97 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Apolipoprotein C-II (apoCII) is in found in chylomicrons (large lipoprotein particles absorbed from the gastrointestinal tract) and VLDL (large lipoproteins that are broken down to eventually form LDL). ApoCII activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells.

Function:
Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly.

Subcellular Location:
Secreted.

Tissue Specificity:
Secreted in plasma.

DISEASE:
Hyperlipoproteinemia 1B (HLPP1B) [MIM:207750]: Autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the apolipoprotein C2 family.

SWISS:
P02655

Gene ID:
344

Database links:

Entrez Gene: 344 Human

Omim: 608083 Human

SwissProt: P18658 Cynomolgus Monkey

SwissProt: P02655 Human

Unigene: 75615 Human




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