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Rabbit Anti-SEMG2  antibody (bs-4488R)
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產(chǎn)品編號 bs-4488R
英文名稱 Rabbit Anti-SEMG2  antibody
中文名稱 精液凝固蛋白2抗體
別    名 Semenogelin 2; Semenogelin II; Semenogelin-2; SEMG2; SEMG2_HUMAN; SGII.  
研究領域 細胞生物  發(fā)育生物學  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEMG2 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015]

Function:
Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.

Subcellular Location:
Secreted.

Tissue Specificity:
Seminal vesicles, and to a much lesser extent, epididymis.

Post-translational modifications:
Semenogelin-2 is thought to form both the 71 kDa polypeptide and, in its glycosylated form, the 76 kDa polypeptide.

Similarity:
Belongs to the semenogelin family.

SWISS:
Q02383

Gene ID:
6407

Database links:

Entrez Gene: 6407 Human

Entrez Gene: 20942 Mouse

Omim: 182141 Human

SwissProt: Q02383 Human

Unigene: 537218 Human



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