| 產(chǎn)品編號 | bs-12672R |
| 英文名稱 | Rabbit Anti-TMPRSS11D antibody |
| 中文名稱 | 跨膜絲氨酸蛋白酶11D抗體 |
| 別 名 | Airway trypsin like protease; Airway trypsin-like protease; HAT; MGC150587; MGC150588; TM11D_HUMAN; TMPRSS11D; Transmembrane protease serine 11D; Transmembrane protease serine 11D catalytic chain; Transmembrane protease serine 11D precursor. |
| 研究領(lǐng)域 | 細(xì)胞生物 跨膜蛋白 泛素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46kDa |
| 細(xì)胞定位 | 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TMPRSS11D: 21-120/418 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008] Function: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Subcellular Location: Secreted. Activated by cleavage and secreted and Cell membrane. Activated by cleavage and secreted. Tissue Specificity: Located in the cells of the submucosal serous glands of the bronchi and trachea. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Contains 1 SEA domain. SWISS: O60235 Gene ID: 9407 Database links: Entrez Gene: 9407 Human Omim: 605369 Human SwissProt: O60235 Human Unigene: 132195 Human |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TM11D) Polyclonal Antibody, Unconjugated (bs-12672R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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