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Rabbit Anti-MYO10  antibody (bs-19153R)  
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產(chǎn)品編號 bs-19153R
英文名稱 Rabbit Anti-MYO10  antibody
中文名稱 肌凝蛋白X抗體
別    名 AW048724; D15Ertd600e; FLJ10639; FLJ21066; FLJ22268; FLJ43256; KIAA0799; MGC131988; mKIAA0799; MYO10; MYO10_HUMAN; Myosin X; Myosin-X; OTTMUSP00000022066; Unconventional myosin 10; Unconventional myosin X; Unconventional myosin-10.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 237 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MYO10: 551-650/2058 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]

Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Plays a role in regions of dynamic actin.

Subunit:
May be in an inactive, monomeric conformation in the cytosol. Detected in cytoplasmic punctae and in cell projections. Colocalizes with actin fibers. Undergoes forward and rearward movements within filopodia. Interacts with microtubules.

Similarity:
Contains 1 FERM domain. Contains 3 IQ domains. Contains 1 myosin head-like domain.
Contains 1 MyTH4 domain.
Contains 2 PH domains.


SWISS:
Q9HD67

Gene ID:
4651

Database links:

Entrez Gene: 281935 Cow

Entrez Gene: 4651 Human

Entrez Gene: 17909 Mouse

Omim: 601481 Human

SwissProt: P79114 Cow

SwissProt: Q9HD67 Human

SwissProt: F8VQB6 Mouse

Unigene: 481720 Human



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