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Rabbit Anti-ITPRIPL1  antibody (bs-17187R)
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產(chǎn)品編號 bs-17187R
英文名稱 Rabbit Anti-ITPRIPL1  antibody
中文名稱 ITPRIPL1蛋白抗體
別    名 Inositol 1,4,5 triphosphate receptor interacting protein like 1; IPIL1; KIAA1754 like; KIAA1754L.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 61kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ITPRIPL1: 25-100/555 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 ITPRIPL1 is a 555 amino acid protein belonging to the ITPRIP family. ITPRIPL1 is a single-pass type I membrane protein expressed as two isoforms produced by alternative splicing events. The gene that encodes ITPRIPL1 maps to human chromosome 2, the second largest human chromosome, consisting of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. It has been hypothesized that human chromosome 2 is the result of an ancient fusion of two ancestral chromosome due to its composition of a vestigial second centromere and vestigial telomeres.

Function:
The function remains unknown. There are two named isoforms.

Subcellular Location:
Membrane; Single-pass type I membrane protein

Similarity:
Belongs to the ITPRIP family.

SWISS:
Q6GPH6

Gene ID:
150771

Database links:

Entrez Gene: 150771 Human

Entrez Gene: 73338 Mouse

Entrez Gene: 499885 Rat

SwissProt: Q6GPH6 Human

SwissProt: A2ASA8 Mouse

SwissProt: Q66H52 Rat



產(chǎn)品圖片
Sample: Panc-1(Human) Cell Lysate at 30 ug Primary: Anti-ITPRIPL1 (bs-17187R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 61 kD
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