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KCNS2 Rabbit pAb (bs-16917R)  
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產品編號 bs-16917R
英文名稱 KCNS2 Rabbit pAb
中文名稱 電壓門控鉀通道亞基KV9.2抗體
別    名 Delayed rectifier K(+) channel alpha subunit 2; Delayed-rectifier K(+) channel alpha subunit 2; Kcns2; KCNS2_HUMAN; KIAA1144; KV9.2; Potassium voltage gated channel subfamily S member 2; Potassium voltage-gated channel subfamily S member 2; Voltage gated   
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 54 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNS2: 401-477/477 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming ?subunits (KV), which include the KV1, KV2, KV3, KV4 and KV9 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV9.2 is a K+ channel subunit that reduces the ion flow and regulates channel activity. It localizes to the cell membrane and, in the absence of KCNB1, KV9.2 may not reach the plasma membrane and may remain in an intracellular compartment.

Function:
Potassium channel subunit. Modulates channel activity and reduces the ion flow.

Subcellular Location:
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.

Tissue Specificity:
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.2/KCNS2 sub-subfamily.

SWISS:
Q9ULS6

Gene ID:
3788

Database links:

Entrez Gene: 3788 Human

Entrez Gene: 16539 Mouse

Entrez Gene: 66022 Rat

Omim: 602906 Human

SwissProt: Q9ULS6 Human

SwissProt: O35174 Mouse

SwissProt: Q9ER26 Rat

Unigene: 388045 Human

Unigene: 71045 Mouse

Unigene: 64498 Rat



產品圖片
Sample: Cerebellum (Mouse) Lysate at 40 ug Primary: Anti-KCNS2 (bs-16917R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD
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