| 產(chǎn)品編號(hào) | bs-16409R |
| 英文名稱 | Rabbit Anti-ZPBP2 antibody |
| 中文名稱 | 透明帶結(jié)合蛋白2抗體 |
| 別 名 | MGC41930; Zona pellucida binding protein 2; Zona pellucida binding protein like; Zona pellucida-binding protein 2; ZPBP-like protein; Zpbp2; ZPBP2_HUMAN; ZPBPL. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 細(xì)胞類型標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZPBP2: 51-150/338 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammalian gametes recognize each other when the plasma membrane of the sperm head binds to the zona pellucida (ZP), an extracellular coat surrounding eggs. The zona pellucida is composed of four major glycoproteins expressed in oocytes, ZP1, ZP2, ZP3 and ZP4. Important receptors of zona pellucida on sperm are the zona pellucida binding proteins (ZPBPs). ZPBPs are suggested to play an essential role in sperm-egg interaction. ZPBP2 (zona pellucida binding protein 2), also known as ZPBPL, is a 338 amino acid secreted protein that belongs to the zona pellucida-binding protein Sp38 family. Mutations in the gene encoding ZPBP2 may cause subfertility. ZPBP2 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 17q12. Function: May be implicated in gamete interaction during fertilization. Subcellular Location: Secreted. Similarity: Belongs to the zona pellucida-binding protein Sp38 family. SWISS: Q6X784 Gene ID: 124626 Database links: Entrez Gene: 124626 Human SwissProt: Q6X784 Human Unigene: 367245 Human |
