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Rabbit Anti-EGFL6  antibody (bs-13062R)
~~~促銷代碼KT202410~~~
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產(chǎn)品編號 bs-13062R
英文名稱 Rabbit Anti-EGFL6  antibody
中文名稱 表皮生長因子樣蛋白6抗體
別    名 EGF like domain multiple 6; EGF repeat containing protein 6; EGF-like protein 6; EGF-like-domain multiple 6; egfl6; EGFL6_HUMAN; epidermal growth factor like protein 6; Epidermal growth factor-like protein 6; MAEG; MAM and EGF domain containing; MAM and EGF domains containing gene protein; MAM and EGF domains-containing gene protein; W80.  
研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學  生長因子和激素  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 59kDa
細胞定位 細胞膜 細胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EGFL6: 231-330/553 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the epidermal growth factor(EGF) repeat superfamily. Members of this superfamily arecharacterized by the presence of EGF-like repeats and are ofteninvolved in the regulation of cell cycle, proliferation, anddevelopmental processes. The gene product contains a signalpeptide, suggesting that it is secreted; an EGF repeat regionconsisting of 4 complete EGF-like repeats and 1 partial EGF-likerepeat, 3 of which have a calcium-binding consensus sequence; anarg-gly-asp integrin association motif; and a MAM domain, which isbelieved to have an adhesive function. This gene is expressed earlyduring development, and its expression has been detected in lungand meningioma tumors. [provided by RefSeq, Jul 2008].

Function:
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.

Subcellular Location:
Secreted, extracellular space, extracellularmatrix, basement membrane (By similarity).

Similarity:
Belongs to the nephronectin family.
Contains 5 EGF-like domains.
Contains 1 MAM domain.

SWISS:
Q8IUX8

Gene ID:
25975

Database links:

Entrez Gene: 25975 Human

Entrez Gene: 54156 Mouse

Entrez Gene: 317470 Rat

Omim: 300239 Human

SwissProt: Q8IUX8 Human

SwissProt: Q9JJZ5 Mouse



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