| 產(chǎn)品編號(hào) | bs-12933R |
| 英文名稱 | Rabbit Anti-CTRB1 antibody |
| 中文名稱 | 胰凝乳蛋白酶B抗體 |
| 別 名 | Chymotrypsinogen B; Chymotrypsinogen B1; ChymotrypsinogenB; ChymotrypsinogenB1; CTRB 1; CTRB; FLJ42412; MGC88037; OTTHUMP00000214638； CTRB1_HUMAN; Chymotrypsin B chain B. |
| 研究領(lǐng)域 | 細(xì)胞生物 新陳代謝 泛素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Chymotrypsin B chain B: 121-230/263 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Chymotrypsins are digestive enzymes that can perform proteolysis by cleaving peptides at the carboxyl side of tyrosine, tryptophan, leucine and phenylalanine, although over time they can also hydrolyze other amide bonds, especially those with leucine-donated carboxyls. Chymotrypsins cleave peptide bonds by attacking the non-reactive carbonyl group with a powerful nucleophile, which momentarily becomes covalently bonded to the substrate to form an intermediate. Chymotrypsin B (CTRB1) and Chymotrypsin B2 (CTRB2) are synthesized in the pancreas by protein biosynthesis as precursors that are enzymatically inactive, but become active as three polypeptide molecules that are interconnected by disulfide bonds. Function: CTRB1 (Chymotrypsinogen B1) is the inactive precursor of Alpha chymotrypsin, one of a family of serine proteases secreted into the gastrointestinal tract. The zymogen is activated by proteolytic cleavage by trypsin. Subcellular Location: Secreted, extracellular space. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. SWISS: P17538 Gene ID: 1504 Database links: Entrez Gene: 1504 Human Entrez Gene: 66473 Mouse Omim: 118890 Human SwissProt: P17538 Human SwissProt: Q9CR35 Mouse |
