| 產(chǎn)品編號(hào) | bs-12084R |
| 英文名稱 | Rabbit Anti-GABRR1 antibody |
| 中文名稱 | G氨基丁酸A型受體rho1/GABAA Rρ1抗體 |
| 別 名 | bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1); GABA(A) receptor subunit rho-1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid (GABA) A receptor rho-1; gamma-aminobutyric acid (GABA) receptor rho 1; Gamma-aminobutyric acid receptor subunit rho-1; MGC163216; GBRR1_HUMAN. |
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Specific References (1) | bs-12084R has been referenced in 1 publications.
[IF=2.47] Kosonsiriluk, Sunantha, et al. "Enhanced GABAergic inhibition in the premammillary nucleus of photorefractory turkey hens via GABA A receptor upregulation." General and Comparative Endocrinology (2016). IHC-P ;
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| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GABRR1: 201-300/479 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] Function: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand gated chloride channels. GABRR1 is a member of the rho subunit family Subunit: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1 Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; Multipass membrane protein. Cell membrane; Multipass membrane protein. Tissue Specificity: Highly expressed in the retina and in a lesser extent in brain, lung and thymus. Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. SWISS: P24046 Gene ID: 2569 Database links: Entrez Gene: 2569 Human Omim: 137161 Human SwissProt: P24046 Human Unigene: 99927 Human |
| 產(chǎn)品圖片 |
Sample:
Eye (Mouse) Lysate at 40 ug
Heart (Mouse) Lysate at 40 ug
HepG2 (Human) Lysate at 30 ug
Primary: Anti-GABRR1 (bs-12084R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
25 ug total protein per lane of various lysates (see on figure) probed with GABRR1 polyclonal antibody, unconjugated (bs-12084R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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