| 產(chǎn)品編號(hào) | bs-11515R |
| 英文名稱 | ENTPD2 Rabbit pAb |
| 中文名稱 | CD39樣蛋白1抗體 |
| 別 名 | CD39 antigen like 1; CD39 antigen-like 1; CD39 like1; CD39L1; CD39like1; ecto ATP diphosphohydrolase 2; ecto ATPase 2; ecto ATPDase 2; Ecto-ATP diphosphohydrolase 2; Ecto-ATPase 2; Ecto-ATPDase 2; ectoATPase 2; ectoATPDase 2; Ectonucleoside triphosphate diphosphohydrolase 2; ENTP2_HUMAN; Entpd2; NTPDase 2; NTPDase2. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Sheep,Cow,Chicken) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ENTPD2/CD39L1: 401-495/495 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events. Function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes. Similarity: Belongs to the GDA1/CD39 NTPase family. SWISS: Q9Y5L3 Gene ID: 954 Database links: Entrez Gene: 954 Human Entrez Gene: 12496 Mouse Omim: 602012 Human SwissProt: Q9Y5L3 Human SwissProt: O55026 Mouse Unigene: 123036 Human Unigene: 482100 Mouse Unigene: 8276 Rat |
| 產(chǎn)品圖片 |
Sample:
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti- ENTPD2 (bs-11515R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
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