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Rabbit Anti-Carboxypeptidase H  antibody (bs-6478R)  
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產(chǎn)品編號(hào) bs-6478R
英文名稱 Rabbit Anti-Carboxypeptidase H  antibody
中文名稱 胰羧肽酶E抗體
別    名 Carboxypeptidase E; Carboxypeptidase-E; Carboxypeptidase H; Carboxypeptidase H precursor; CarboxypeptidaseE; CarboxypeptidaseH; CBPE_HUMAN; CPE; Cph 1; CPH; Cph1; Enkephalin convertase; Entephalin convertase; Prohormone processing carboxypeptidase; Prohormone-processing carboxypeptidase.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  糖尿病  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Carboxypeptidase E: 201-300/476 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.

Subcellular Location:
Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
soform 2: Nucleus.

Tissue Specificity:
Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas.

Similarity:
Belongs to the peptidase M14 family.

SWISS:
P16870

Gene ID:
1363

Database links:

Entrez Gene: 1363 Human

Entrez Gene: 12876 Mouse

Entrez Gene: 25669 Rat

Omim: 114855 Human

SwissProt: P04836 Cow

SwissProt: P16870 Human

SwissProt: Q00493 Mouse

SwissProt: P15087 Rat

Unigene: 75360 Human

Unigene: 31395 Mouse

Unigene: 470333 Mouse

Unigene: 7149 Rat



產(chǎn)品圖片
Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti- Carboxypeptidase H (bs-6478R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD
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