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產(chǎn)品編號(hào) bs-6801R
英文名稱(chēng) Rabbit Anti-TCERG1  antibody
中文名稱(chēng) 轉(zhuǎn)錄延伸調(diào)節(jié)蛋白1抗體
別    名 CA 150; Co activator of 150 kDa; Coactivator of 150 kDa; MGC133200; TAF 2S; TAF2S; TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD; TATA box binding protein associated factor 2S; TATA box binding protein associated factor RNA polymerase II S 150kD; TCERG 1; TCERG1; Transcription elongation regulator 1; Transcription factor CA 150; Transcription factor CA150; TCRG1_HUMAN.  
研究領(lǐng)域 腫瘤  轉(zhuǎn)錄調(diào)節(jié)因子  腫瘤細(xì)胞生物標(biāo)志物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 124kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TCERG1/CA150: 701-800/1098 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 CA150 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. It interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain.

Function:
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.

Subunit:
Binds formin (By similarity). Binds RNA polymerase II, HD and SF1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Detected in brain neurons.

Similarity:
Contains 6 FF domains.

SWISS:
O14776

Gene ID:
10915

Database links:

Entrez Gene: 10915 Human

Entrez Gene: 56070 Mouse

Entrez Gene: 63838 Rat

Omim: 605409 Human

SwissProt: O14776 Human

SwissProt: Q8CGF7 Mouse

Unigene: 443465 Human

Unigene: 723884 Human

Unigene: 270511 Mouse



產(chǎn)品圖片
Sample: Testis(Mouse) Lysate at 40 ug Primary: Anti-TCERG1 (bs-6801R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 124 kD Observed band size: 124kD
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti- TCERG1 (bs-6801R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 124 kD Observed band size:124 kD
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