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Rabbit Anti-THRSP  antibody (bs-6738R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-6738R
英文名稱 Rabbit Anti-THRSP  antibody
中文名稱 甲狀腺激素反應蛋白抗體
別    名 Lpgp; LPGP1; S14; S14 protein; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein; Thyroid hormone responsive (SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein; Thyroid hormone responsive SPOT14; Thyroid hormone-inducible hepatic protein.  
研究領域 腫瘤  細胞生物  信號轉導  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Rabbit)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human THRSP: 116-145/146 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.Mainly expressed in tissues that synthesize triglycerides.

Function:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

Subunit:
Homodimer. Heterodimer with MID1IP1. Interacts with THRB and PLAGL1.

Subcellular Location:
Cytoplasm.Nucleus.

Tissue Specificity:
Mainly expressed in tissues that synthesize triglycerides.

Similarity:
Mainly expressed in tissues that synthesize triglycerides.
Belongs to the SPOT14 family.

SWISS:
Q92748

Gene ID:
7069

Database links:

Entrez Gene: 7069 Human

Entrez Gene: 21835 Mouse

Entrez Gene: 25357 Rat

Omim: 601926 Human

SwissProt: Q92748 Human

SwissProt: Q62264 Mouse

SwissProt: P04143 Rat

Unigene: 591969 Human

Unigene: 28585 Mouse

Unigene: 81140 Rat



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (THRSP) Polyclonal Antibody, Unconjugated (bs-6738R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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