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Rabbit Anti-SH2D2A  antibody (bs-3858R)
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產品編號 bs-3858R
英文名稱 Rabbit Anti-SH2D2A  antibody
中文名稱 血管內皮生長因子受體相關蛋白抗體
別    名 SH2D2A/VEGF receptor associated protein SCAP; SH2 domain containing adapter protein; SH2 domain containing protein 2A; SH2 domain protein 2A; T cell specific adapter protein; T cell specific adapter protein TSAd; T cell specific adpater protein TSAd; T lymphocyte specific adaptor protein; TSAd; VEGF receptor associated protein; VRAP.   
Specific References  (1)     |     bs-3858R has been referenced in 1 publications.
[IF=12.35] Compeer et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. (2018) Nat.Commun. 9:1597  IF ;  Mouse.  
研究領域 腫瘤  免疫學  生長因子和激素  血管內皮細胞  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1μg /Test,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 43kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH2D2A: 101-200/389 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 SH2D2A is thought to be a T-cell-specific adapter protein involved in the control of T-cell activation. It may play a role in the CD4-p56-LCK-dependent signal transduction pathway and also in normal and pathological angiogenesis.

Subunit:
Interacts with KDR. Interacts with TXK and ITK.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
SH2D2A is thought to be a T-cell-specific adapter protein involved in the control of T-cell activation. It may play a role in the CD4-p56-LCK-dependent signal transduction pathway and also in normal and pathological angiogenesis.

Similarity:
Contains 1 SH2 domain.

SWISS:
Q9NP31

Gene ID:
9047

Database links:

Entrez Gene: 9047 Human

Entrez Gene: 27371 Mouse

Omim: 604514 Human

SwissProt: Q9NP31 Human

SwissProt: Q9QXK9 Mouse

Unigene: 103527 Human

Unigene: 86361 Mouse



產品圖片
Blank control(blue): HUVEC cells(fixed with 2% paraformaldehyde (10 min),then permeabilized with 90% ice-cold methanol for 30 min on ice). Primary Antibody:Rabbit Anti- SH2D2A antibody(bs-3858R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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