| 產(chǎn)品編號 | bs-1910R |
| 英文名稱 | TGF beta Receptor III Rabbit pAb |
| 中文名稱 | 轉(zhuǎn)移生長因子β受體3抗體 |
| 別 名 | beta glycan; TGF beta R3; betaglycan; betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor beta Receptor III; Transforming growth factor beta receptor III betaglycan 300kDa; TGF-βRⅢ; TGFβRⅢ; TGFβ RIII; TGF β RIII; TGF-β RIII; TGFβ-RIII; Transforming growth factor beta receptor type 3. |
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Specific References (2) | bs-1910R has been referenced in 2 publications.
[IF=5.191] Chao Ye. et al. Naringin in the repair of knee cartilage injury via the TGF-β/ALK5/Smad2/3 signal transduction pathway combined with an acellular dermal matrix. J Orthop Transl. 2021 Aug;: IHC ; Rabbit.
[IF=1.785] Chao Ye. et al. Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects in rabbit knees through the transforming growth factor?β superfamily signaling pathway. Exp Ther Med. 2020 Nov;20(5):1-1 IHC ; Rabbit.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞凋亡 生長因子和激素 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Pig,Sheep,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 94 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TGFBR3: 701-850/850 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]. Function: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Subunit: Interacts with TCTEX1D4. Subcellular Location: Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. Post-translational modifications: Extensively modified by glycosaminoglycan groups (GAG). Similarity: Contains 1 ZP domain. SWISS: Q03167 Gene ID: 7049 Database links: Entrez Gene: 7049 Human Entrez Gene: 21814 Mouse Omim: 600742 Human SwissProt: Q03167 Human SwissProt: O88393 Mouse Unigene: 482390 Human Unigene: 200775 Mous 轉(zhuǎn)化生長因子β受體Ⅲ，TGFβRⅢ |
| 產(chǎn)品圖片 |
Sample:
K562 Cell (Human) Lysate at 40 ug
HepG2 Cell (Human) Lysate at 40 ug
Hela Cell (Human) Lysate at 40 ug
Primary: Anti- TGF beta Receptor III (bs-1910R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 94 kD
Observed band size: 110 kD
Sample:
Lane 1: Mouse Placenta tissue lysates
Lane 2: Mouse Testis tissue lysates
Lane 3: Rat Placenta tissue lysates
Lane 4: Rat Testis tissue lysates
Lane 5: Human HepG2 cell lysates
Lane 6: Human HeLa cell lysates
Lane 7: Human A431 cell lysates
Primary: Anti-TGF beta Receptor III (bs-1910R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 94 kDa
Observed band size: 130 kDa
Independently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (bs-1910R) at 1:250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining
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