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Rabbit Anti-IL20  antibody (bs-1834R)
~~~促銷代碼KT202410~~~
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產(chǎn)品編號 bs-1834R
英文名稱 Rabbit Anti-IL20  antibody
中文名稱 白細(xì)胞介素-20抗體
別    名 Interleukin-20; four alpha helix cytokine; IL10D; Interleukin 20; Interleukin-20; ZCYTO10; IL20_MOUSE; Cytokine Zcyto10; IL-20; IL20_HUMAN; MGC96907; UNQ852/PRO1801.  
研究領(lǐng)域 免疫學(xué)  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-20: 51-150/176 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.

Function:
Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed at very low levels in skin, trachea, and other tissues.

Similarity:
Belongs to the IL-10 family.

SWISS:
Q9JKV9

Gene ID:
58181

Database links:

Entrez Gene: 50604 Human

Entrez Gene: 58181 Mouse

SwissProt: Q9NYY1 Human

SwissProt: Q9JKV9 Mouse



白介素20是新發(fā)現(xiàn)的細(xì)胞因子,屬于白介素10家族成員。它可由活化的外周血單一核細(xì)胞和角質(zhì)形成細(xì)胞產(chǎn)生。與其他白介素10家族成員的受體亞單位有交叉反應(yīng),多用于銀屑病及風(fēng)濕病的研究。
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat skin tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-20) Polyclonal Antibody, Unconjugated (bs-1834R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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