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Synaptotagmin-4 Rabbit pAb (bs-1897R)  
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產(chǎn)品編號 bs-1897R
英文名稱 Synaptotagmin-4 Rabbit pAb
中文名稱 突觸結(jié)合蛋白4抗體
別    名 SYT4_HUMAN; Syt4; SytIV; HsT1192; KIAA1342; Synaptotagmin IV; SYT4; SYT 4; Syt IV; SytIV; Synaptotagmin4; SynaptotagminIV.  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptotagmin-4: 301-400/425 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the synaptotagmin family. Members of this family are multi-domained, integral membrane proteins of synaptic vesicles, and are thought to serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. This gene is primarily expressed in the nervous tissues. [provided by RefSeq].

Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.

Tissue Specificity:
Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.

Similarity:
Belongs to the synaptotagmin family.
Contains 2 C2 domains.

SWISS:
Q9H2B2

Gene ID:
6860

Database links:

Entrez Gene: 6860 Human

Omim: 600103 Human

SwissProt: Q9H2B2 Human

Unigene: 8059 Human



產(chǎn)品圖片
Sample: Lane1:Brain(Mouse) Lysate at 30 ug Lane2:Heart(Mouse) Lysate at 30 ug Primary: Anti-SYNAPTOTAGMIN-4(bs-1897R) at 1:200 dilution; Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1:3000 dilution; Predicted band size : 48kD Observed band size : 47kD
Sample: Cerebellum (Mouse) Lysate at 40 ug Cerebrum (Rat) Lysate at 40 ug Cerebral cortex (Mouse) Lysate at 40 ug Hippocampus (Mouse) Lysate at 40 ug Primary: Anti- Synaptotagmin-4 (bs-1897R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 50 kD
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