| 產(chǎn)品編號(hào) | bs-1200R |
| 英文名稱 | Omgp Rabbit pAb |
| 中文名稱 | 少突細(xì)胞髓磷脂糖蛋白抗體 |
| 別 名 | olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN. |
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Specific References (1) | bs-1200R has been referenced in 1 publications.
[IF=1.27] Feng, Nianping, et al. "Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin?associated inhibitor expression and neural apoptosis." Experimental and Therapeutic Medicine. IHC-P ; Rat.
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| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Omgp: 166-280/440 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin. Function: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. Subunit: Binds to RTN4R. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Oligodendrocytes and myelin of the central nervous system. Post-translational modifications: O-glycosylated in its Ser/Thr-rich repeat domain (Potential). Similarity: Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. SWISS: P23515 Gene ID: 4974 Database links: Entrez Gene: 4974 Human Entrez Gene: 100172122 Orangutan Omim: 164345 Human SwissProt: P23515 Human Unigene: 113874 Human OMgp也是髓鞘糖蛋白的一種，在發(fā)育期促進(jìn)軸突生長,成熟期抑制軸突生長.其抑制作用主要由髓鞘來源的抑制分子的共同受體NgR介導(dǎo),在神經(jīng)營養(yǎng)因子受體p75NTR以及小GTP酶Rho等信號(hào)分子的共同參與下完成. |
| 產(chǎn)品圖片 |
Sample: Medulla (Mouse) Lysate at 30 ug
Primary: Anti- Omgp (bs-1200R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 49 kD
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Cerebellum tissue lysates
Lane 3: Rat Cerebrum tissue lysates
Lane 4: Rat Cerebellum tissue lysates
Primary: Anti-Omgp (bs-1200R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kDa
Observed band size: 48 kDa
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