| 產(chǎn)品編號(hào) | bsm-61798R |
| 英文名稱 | Sprouty 2 Recombinant Rabbit mAb |
| 中文名稱 | 快速發(fā)育生長(zhǎng)因子同源蛋白2重組兔單抗 |
| 別 名 | hSPRY2; Sprouty2; SPRY2. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 35 kDa |
| 檢測(cè)分子量 | 42 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Spry 2: 250-315 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2.Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis. SWISS: O43597 Gene ID: 10253 Sprouty2是一類在全身組織廣泛表達(dá)的軟脂?；椎鞍?在機(jī)體的信號(hào)轉(zhuǎn)導(dǎo),尤其是受體蛋白對(duì)受體酪氨酸激酶(RTK)等信號(hào)通路起著重要的抑制作用,其表達(dá)在多種腫瘤組織中發(fā)生明顯下降,并可進(jìn)一步引起細(xì)胞異常增殖、轉(zhuǎn)化及新生血管形成,從而促進(jìn)腫瘤的發(fā)生及發(fā)展。 |
| 產(chǎn)品圖片 |
Western blot analysis of HeLa cell lysate. Using Sprouty 2 (bsm-61798R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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