產(chǎn)品編號(hào) | bsm-61732R |
英文名稱 | beta Defensin 1 Recombinant Rabbit mAb |
中文名稱 | 防御素β1/Defensin β1重組兔單抗 |
別 名 | BD1; beta 1; DEFB1; DEFB101; Defensin; Defensin beta 1; HBD1. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 7 kDa |
檢測(cè)分子量 | 7 |
性 狀 | Liquid |
免 疫 原 | A synthesized peptide derived from human beta Defensin 1: 30-68/68 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. SWISS: P60022 Gene ID: 1672 防御素在人體中廣泛分布的,目前已知的α-防御素有6種,研究人員從人體的腎臟、氣管、鼻粘膜與唾液中也發(fā)現(xiàn)了兩種β防御素,在許多器官的上皮細(xì)胞與非上皮組織的細(xì)胞中發(fā)現(xiàn)了β-防御素。防御素的表達(dá)與病原體的入侵是緊密相關(guān)。 |
產(chǎn)品圖片 | |