| 產(chǎn)品編號(hào) | bsm-61721R |
| 英文名稱 | Jab1/COPS5 Recombinant Rabbit mAb |
| 中文名稱 | Jun激活區(qū)域-連接蛋白1重組兔單抗 |
| 別 名 | cops5; CSN 5; CSN5; JAB 1; MGC3149; MOV34; SGN5. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38 kDa |
| 檢測(cè)分子量 | 38 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human COPS5: 10-80 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. SWISS: Q92905 Gene ID: 10987 轉(zhuǎn)錄調(diào)節(jié)因子（Transcriptin Regulators） Jab1是一種多功能蛋白質(zhì),能與多種蛋白發(fā)生相互作用,調(diào)控多種細(xì)胞內(nèi)信號(hào)轉(zhuǎn)導(dǎo)通路。JAB1也可增強(qiáng)多種轉(zhuǎn)錄因子的活性. |
| 產(chǎn)品圖片 |
Western blot analysis of MCF7 cell lysate. Using Jab1/COPS5 (bsm-61721R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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