產(chǎn)品編號(hào) | bsm-61699R |
英文名稱 | CRP Recombinant Rabbit mAb |
中文名稱 | C-反應(yīng)蛋白重組兔單抗 |
別 名 | CRP; Pentraxin 1; PTX1; C reactive protein pentraxin related. |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Recombinant |
克 隆 號(hào) | 20F17 |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB=1:500-1:2000,IHC-P=1:50-1:200,IHC-F=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 25 kDa |
檢測(cè)分子量 | 25 |
性 狀 | Liquid |
免 疫 原 | A synthesized peptide derived from human C reactive protein: 201-224/224 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. SWISS: P02741 Gene ID: 1401 C反應(yīng)蛋白 CRP(C-reactive protin)是與C性肺炎球菌的多糖起反應(yīng)的一種蛋白,在某些細(xì)菌的感染過(guò)程中出現(xiàn)在血漿中。 CRP是在一些病理性情況下出現(xiàn)于病人血清中的一種糖蛋白,特別是在伴有肯炎癥和組織壞死疾病的急性期。血清中出現(xiàn)的這種異常蛋白能和肺炎C-多糖體發(fā)生沉淀反應(yīng),當(dāng)疾病好轉(zhuǎn)或緩解時(shí),CRP減低或消失。 臨床意義: (1)各種急性化膿性炎癥、菌血癥、組織壞死(心肌梗塞、手術(shù)、嚴(yán)重創(chuàng)傷、燒傷等)、惡性腫瘤、結(jié)締組織病、腎移殖后急性排異反應(yīng)、急性風(fēng)濕熱、風(fēng)濕性關(guān)節(jié)炎、類(lèi)風(fēng)濕性關(guān)節(jié)炎、心 |
產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with CRP monoclonal antibody, unconjugated (bsm-61699R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CRP Monoclonal Antibody, Unconjugated (bsm-61699R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CRP Monoclonal Antibody, Unconjugated (bsm-61699R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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