| 產(chǎn)品編號 | bsm-61510R |
| 英文名稱 | GLUT3 Recombinant Rabbit mAb |
| 中文名稱 | 葡萄糖轉(zhuǎn)運(yùn)蛋白3重組兔單抗 |
| 別 名 | brain; Glucose transporter type 3; GLUT3; Slc2a3. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 9A18 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54 kDa |
| 檢測分子量 | 54 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human GLUT3: 10-52 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. SWISS: P11169 Gene ID: 6515 交換和轉(zhuǎn)運(yùn)（Trafficking and Transport） GLUT-3屬于溶質(zhì)運(yùn)載蛋白家族成員（solute carrier family），主要功能是轉(zhuǎn)載葡萄糖進(jìn)入上皮細(xì)胞。 目前主要用于糖尿病腎病和視網(wǎng)膜病變的研究，也是腎小球系膜細(xì)胞上的主要葡萄糖轉(zhuǎn)運(yùn)體。GLUT3的功能狀態(tài)直接影響系膜細(xì)胞的糖代謝及功能變化。 近期，研究人員也用來區(qū)別一些良、惡性腫瘤的鑒別。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with GLUT3 monoclonal antibody, unconjugated (bsm-61510R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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