產(chǎn)品編號(hào) | bsm-61501R |
英文名稱 | Aggrecan Recombinant Rabbit mAb |
中文名稱 | 軟骨蛋白聚糖重組兔單抗 |
別 名 | ACAN; AGC1; AGCAN; Aggrecan 1; CSPG1; CSPGCP; JSCATE; Large aggregating proteoglycan; mcspg; mgsk16; MSK 16; SEDK. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 261 kDa |
檢測(cè)分子量 | 250 |
性 狀 | Liquid |
免 疫 原 | A synthesized peptide derived from human Aggrecan: 700-900/2530 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. SWISS: P16112 Gene ID: 176 Aggrecan是軟骨細(xì)胞外基質(zhì)的主要結(jié)構(gòu)成分之一。它與膠原蛋白網(wǎng)絡(luò)結(jié)合,維持軟骨彈性、緩沖壓力,承擔(dān)負(fù)荷,并有自我潤(rùn)滑的性能。蛋白多糖的進(jìn)行性喪失是骨性關(guān)節(jié)病發(fā)病主要原因之一。 |